{"id":128554,"date":"2023-07-28T11:16:02","date_gmt":"2023-07-28T11:16:02","guid":{"rendered":"https:\/\/casadicurasanrossore.it\/clinical-pharmacology\/"},"modified":"2023-09-21T09:08:54","modified_gmt":"2023-09-21T09:08:54","slug":"clinical-pharmacology","status":"publish","type":"page","link":"https:\/\/casadicurasanrossore.it\/en\/diagnosis-and-care\/specialist-units\/medical-activities\/clinical-pharmacology\/","title":{"rendered":"Clinical Pharmacology"},"content":{"rendered":"

[vc_row row_height_percent=”0″ override_padding=”yes” h_padding=”2″ top_padding=”3″ bottom_padding=”3″ back_color=”color-xsdn” overlay_alpha=”50″ gutter_size=”4″ column_width_percent=”100″ shift_y=”0″ z_index=”0″ uncode_shortcode_id=”296199″ back_color_type=”uncode-palette”][vc_column column_width_percent=”100″ position_vertical=”middle” gutter_size=”3″ style=”light” font_family=”font-136269″ overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ css_animation=”alpha-anim” animation_speed=”1000″ width=”1\/1″ uncode_shortcode_id=”163701″][vc_row_inner][vc_column_inner column_width_percent=”100″ gutter_size=”3″ overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”4″ mobile_width=”0″ width=”1\/1″][vc_custom_heading text_color=”color-wayh” heading_semantic=”h6″ text_size=”fontsize-160000″ text_transform=”uppercase” text_space=”fontspace-135905″ css_animation=”parallax” parallax_intensity=”1″ uncode_shortcode_id=”570228″ text_color_type=”uncode-palette”]Medical activities<\/a>[\/vc_custom_heading][vc_custom_heading text_color=”color-nhtu” text_font=”font-207245″ text_size=”fontsize-155944″ text_weight=”400″ text_transform=”uppercase” text_height=”fontheight-179065″ sub_lead=”yes” css_animation=”parallax” parallax_intensity=”2″ uncode_shortcode_id=”140490″ text_color_type=”uncode-palette”]Clinical Pharmacology[\/vc_custom_heading][\/vc_column_inner][\/vc_row_inner][vc_column_text uncode_shortcode_id=”211786″]Clinical Pharmacology plays a crucial role in the rationalization of drug therapies and prescriptive appropriateness, in terms of efficacy and safety. The main purpose of this discipline is to harmonize and personalize complex specialized therapies with an overview that allows the setting of rational drug treatment.<\/p>\n

An increasing number of patients are taking polypharmacy: 30% of patients>65 years old takes an average of 5 drugs at the same time. As a result, the risk of toxicity from drug interactions is high (Naples JG et al, J Am Geriatr Soc. 2016<\/em>), representing in Western countries the reason for ER access in more than 30% of cases (Castro I et al., Int J Clin Pharm. 2013; Viktil KK et al. Br J Clin Pharmacol 2007<\/em>), especially during treatment with cardiovascular<\/strong> and hypertension<\/strong> drugs (beta-blockers, diuretics, ACE inhibitors, calcium channel blockers, alpha blockers, sartans, antiplatelets and anticoagulants), antibiotics, analgesics, antidiabetics, central nervous system drugs<\/strong> (antidepressants, neuroleptics, benzodiazepines) (Gurwitz JH et al., JAMA 2003<\/em>) and anticancer drugs<\/strong>.<\/p>\n

According to data from the World Health Organization<\/a> (click to view the site in ENG), at least 60 percent of adverse reactions are preventable, due to incorrect prescription, dispensing or intake of drugs, genetic and environmental influences, increasingly frequent self-medication by the patient himself, increasing use of counterfeit or uncontrolled drugs available on the Web, and interaction with other drugs, herbal products or simple foods.
\nThe clinical pharmacologist is responsible for accurately assessing the following aspects of a drug therapy:<\/p>\n